Aiding gastrointestinal diagnostic laboratory by designing a device for the non invasive detection of peptic ulcer

Proc Inst Mech Eng H. 2023 Aug;237(8):928-935. doi: 10.1177/09544119231184111. Epub 2023 Jun 27.

Abstract

Peptic ulcer (PU) has been recognized as an utmost gastrointestinal problem that affects the lining of the stomach and duodenum, specifically triggering soreness. It is a life-threatening condition, while roots of the infection are not identified yet. There are various risk factors for the cause of peptic ulcer disease, but the most significant is "Helicobacter pylori" (H. pylori). The detection of this disease involves different invasive procedures which are painful and not feasible for everyone. The aim of this device is to identify the peptic ulcer non-invasively by unmasking the presence of H. Pylori bacterium by monitoring crucial parameters of the disease which include respiration rate, heart rate, ECG, pH of Saliva, and temperature. Multiple investigations related to PU authenticate the alteration in these physicochemical aspects of the body. The increase in the level of stomach acid in PU is responsible for belching and bloating. Heart rate, temperature, and respiratory rate are also elevated during peptic ulcers while the pH of Saliva is decreased toward the acidic side. The disturbance in the QRS complex of the ECG wave is also observed. These biosignals are examined as analog input from the body, sent into MCP3008, and converted into digital input signals. Then these digital inputs are directed toward Raspberry pi 3 which processes, received inputs, and shows output on the LCD. The values of parameters obtained are then compared with standard values and a conclusion is made that whether a patient has a peptic ulcer or not.

Keywords: Helicobacter pylori; biosignal; duodenum; non-invasive; peptic ulcer; stomach.

MeSH terms

  • Helicobacter Infections* / complications
  • Helicobacter Infections* / diagnosis
  • Helicobacter pylori*
  • Humans
  • Peptic Ulcer* / etiology
  • Peptic Ulcer* / microbiology
  • Risk Factors