New approaches in childhood asthma treatment

Curr Opin Allergy Clin Immunol. 2023 Aug 1;23(4):319-326. doi: 10.1097/ACI.0000000000000922. Epub 2023 Jun 23.

Abstract

Purpose of review: This review aims to summarize the most recent advances in asthma management, focusing on novel approaches to pediatric asthma.

Recent findings: In recent years, the therapeutic tools for pediatric asthma have expanded significantly for both the nonsevere and severe forms. The use of anti-inflammatory treatment, even for the mildest cases, and the withdrawal of symptomatic bronchodilation as monotherapy have been included in the most recent guidelines. Also, different biological therapies have revolutionized the therapeutical approach for severe uncontrolled asthma in children and adolescents.

Summary: With the expanding landscape of novel therapeutic approaches for pediatric asthma, further evidence is needed to help clinicians choose the best option for patients, particularly those with severe asthma. The identification of novel predictive biomarkers may also help pediatricians in selecting children and adolescents for innovative therapies.

Publication types

  • Review

MeSH terms

  • Adolescent
  • Asthma* / drug therapy
  • Biomarkers
  • Child
  • Humans

Substances

  • Biomarkers