Rethinking Vasopressin: New Insights into Vasopressin Signaling and Its Implications

Kidney360. 2023 Aug 1;4(8):1174-1180. doi: 10.34067/KID.0000000000000194. Epub 2023 Jun 26.

Abstract

Vasopressin is a highly conserved peptide hormone that has been traditionally associated with water homeostasis. There is accumulating evidence in both humans and animal models that vasopressin is implicated in the regulation of metabolism. This review focuses on the effects that vasopressin exerts on the regulation of glucose and fatty acids with a particular emphasis on the potential repercussions of metabolic dysregulation in kidney disease.

Publication types

  • Review
  • Research Support, N.I.H., Intramural
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Glucose / metabolism
  • Homeostasis / physiology
  • Humans
  • Signal Transduction*
  • Vasopressins* / metabolism

Substances

  • Vasopressins
  • Glucose