Intradural Extramedullary Tumors and Associated Syndromes

Neuroimaging Clin N Am. 2023 Aug;33(3):407-422. doi: 10.1016/j.nic.2023.03.002. Epub 2023 Apr 25.

Abstract

Most intradural tumors are located within the intradural extramedullary compartment, and the most common tumors are schwannomas and meningiomas. Other less common neoplasms include neurofibroma, solitary fibrous tumor, myxopapillary ependymoma, lymphoma, metastatic leptomeningeal disease, malignant peripheral nerve sheath tumor, and paraganglioma. Patients usually present with gait ataxia, radicular pain, and motor and sensory deficits due to chronic compressive myelopathy or radiculopathy. MRI is the modality of choice for detecting and evaluating intradural extramedullary spinal tumors. This imaging technique helps narrow the differential diagnosis and therefore decide treatment.

Keywords: Cancer; Intradural extramedullary; MRI; Spinal tumors; Spine.

Publication types

  • Review

MeSH terms

  • Humans
  • Magnetic Resonance Imaging / methods
  • Meningeal Neoplasms* / pathology
  • Spinal Cord Neoplasms* / diagnostic imaging
  • Spinal Cord Neoplasms* / pathology
  • Spinal Neoplasms* / pathology
  • Syndrome