Pure squamous cell carcinoma of the pancreas: a rare and challenging diagnosis (case report)

Pan Afr Med J. 2023 May 3:45:4. doi: 10.11604/pamj.2023.45.4.29484. eCollection 2023.

Abstract

Squamous cell carcinoma (SCC) of the pancreas is a rare exocrine ductal tumour with unknown pathophysiology and poor treatment options. We present a case of SCC in a 59-year-old male patient who presented with epigastric pain, vomiting, anorexia, asthenia, and weight loss. Abdomino-pelvic CT revealed a pancreatic mass with adenopathy satellites. Surgical biopsies were negative, and a trans-duodenal gastric endoscopy showed suspicious lymphadenopathies and a hypoechoic lesion invading the portal vein. An anapathological study confirmed SCC at the site of intense necrotic and inflammatory changes. The patient received radio-chemotherapy, but ultimately developed peritoneal carcinoma.

Keywords: Squamous cell carcinoma; case report; endoscopic ultrasonography; pancreas.

Publication types

  • Case Reports

MeSH terms

  • Biopsy
  • Carcinoma, Squamous Cell* / diagnosis
  • Carcinoma, Squamous Cell* / therapy
  • Endoscopy, Gastrointestinal
  • Humans
  • Male
  • Middle Aged
  • Pancreas / pathology
  • Pancreatic Neoplasms* / diagnosis
  • Pancreatic Neoplasms* / therapy