The Role of Lumen Apposing Metal Stents in the Palliation of Distal Malignant Biliary Distal Obstruction

Cancers (Basel). 2023 May 12;15(10):2730. doi: 10.3390/cancers15102730.

Abstract

Malignant biliary obstruction (DMBO) has been traditionally managed by endoscopic retrograde cholangiopancreatography (ERCP). In the case of ERC failure, percutaneous transhepatic biliary drainage (PT-BD) has been widely utilized as a salvage procedure. However, over the last decade, endoscopic ultrasound-guided biliary drainage (EUS-BD) has gained increasing popularity, especially after the advent of electrocautery-enhanced lumen apposing metal stent devices (EC-LAMSs) which enable a one-step procedure, granting prevention of biliary leakage and minimizing occurrence of adverse events (AEs). In parallel, increasing evidence suggests a possible role of EUS-BD in the management of DMBO as a primary palliative drainage modality. In the current paper, we aim to review all the available evidence on the role of EUS-BD performed with EC-LAMSs and discuss salient technical aspects of this type of procedure.

Keywords: biliary obstruction; endoscopic ultrasonography; lumen apposing metal stents (LAMS).

Publication types

  • Review

Grants and funding

This research received no external funding.