Monoclonal gammopathy of uncertain significance
Med Clin (Barc). 2023 Sep 8;161(5):217-224.
doi: 10.1016/j.medcli.2023.05.006.
Epub 2023 Jun 15.
[Article in
English,
Spanish]
Affiliations
- 1 Hospital Universitario de Salamanca/Instituto de Investigación Biomédica de Salamanca (IBSAL)/Centro Investigación del Cáncer-IBMCC (USAL-CSIC), Salamanca, España.
- 2 Hospital Universitario de Salamanca/Instituto de Investigación Biomédica de Salamanca (IBSAL)/Centro Investigación del Cáncer-IBMCC (USAL-CSIC), Salamanca, España. Electronic address: mvmateos@usal.es.
Abstract
Monoclonal gammopathy of uncertain significance is a premalignant plasma cell neoplasm with a high prevalence in the population over 50 years of age and an annual risk of progression of 1%. Multiple recent studies have led to advances in understanding both the pathogenesis of these disorders and their risk of progression to other diseases. Patients require lifelong follow-up, and a multidisciplinary and risk-adapted approach is essential. In recent years, an increasing number of entities associated with a paraprotein, known as clinically significant monoclonal gammopathies, have been recognized.
Keywords:
Gammapatía monoclonal de significado incierto; Monoclonal gammopathy of uncertain significance; Prognosis; Pronóstico; Screening.
Copyright © 2023. Published by Elsevier España, S.L.U.
MeSH terms
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Humans
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Middle Aged
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Monoclonal Gammopathy of Undetermined Significance* / complications
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Monoclonal Gammopathy of Undetermined Significance* / diagnosis
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Monoclonal Gammopathy of Undetermined Significance* / epidemiology
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Multiple Myeloma* / complications
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Paraproteinemias* / complications
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Paraproteinemias* / diagnosis
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Paraproteinemias* / epidemiology