Appearance of retinal arterial macroaneurysms in patients using swept-source optical coherence tomographic angiography

BMC Ophthalmol. 2023 Jun 16;23(1):280. doi: 10.1186/s12886-023-03016-x.

Abstract

Background: Retinal arterial macroaneurysm (RAM) is a common clinical disease leading to vision loss in elderly individuals. The appropriate interpretation of swept-source optical coherence tomographic angiography (SS-OCTA), a noninvasive examination, is easy and convenient for detecting the status of RAMs and guiding treatment.

Methods: The objectives of this study were to describe the morphologic characteristics of RAMs using SS-OCTA and to observe whether there are differences in the morphologies of RAMs between SS-OCTA and fundus fluorescein angiography (FFA), before and after treatment. We retrospectively evaluated twenty-two eyes of 22 patients who were diagnosed with RAMs. All patients underwent a complete ophthalmologic examination, including a review of medical records, best-corrected visual acuity (BCVA), fundus photography, FFA and SS-OCTA. RAMs were recorded by SS-OCTA before any treatment or observation decisions were made. The morphologic findings of the RAMs on SS-OCTA were investigated.

Results: On SS-OCTA, RAMs can show local dilatation or an irregular linear blood flow signal, and the dilated cystic lumen may show thrombosis with a low reflection signal. After treatment, the shape of the RAMs will show reactive changes. The findings on SS-OCTA are not very consistent with those on FFA.

Conclusions: The same RAM may have different manifestations on OCTA and FFA, and OCTA can more conveniently reflect the changes in blood flow signals and treatment response of RAMs.

Keywords: Fluorescein angiography; Optical coherence tomography angiography; Retinal arterial macroaneurysms.

MeSH terms

  • Eye
  • Fluorescein Angiography / methods
  • Humans
  • Retinal Arterial Macroaneurysm*
  • Retinal Vessels / diagnostic imaging
  • Retrospective Studies
  • Tomography, Optical Coherence / methods