Annotated protein network analysis linking oral diseases

Bioinformation. 2022 Aug 31;18(8):724-729. doi: 10.6026/97320630018724. eCollection 2022.

Abstract

Oral cancer is becoming more common, and it threatens to be a serious worldwide medical issue. Hence, it is of interest to elucidate the networks between proteins and biologically active compounds, as well as their functional annotations, and cell signaling pathways. The online STRING software was used to create a molecular genetics interaction network named AZURIN on oral bacterial proteins. We also used the cystoscope software to identify 11 nodes and 16 edges with an average node order of 2.91. Thus, we document data on the interaction of protein networks with other proteins for identifying potential therapeutic drug candidates linked to oral disease.

Keywords: Networking; STRING; bacteria; cystoscope; oral cancer.