A review on circular RNAs and bacterial infections

Int J Biol Macromol. 2023 Jul 31:244:125391. doi: 10.1016/j.ijbiomac.2023.125391. Epub 2023 Jun 14.

Abstract

Bacterial infections and related diseases have been a major burden on social public health and economic stability around the world. However, the effective diagnostic methods and therapeutic approaches to treat bacterial infections are still limited. As a group of non-coding RNA, circular RNAs (circRNAs) that were expressed specifically in host cells and played a key regulatory role have the potential to be of diagnostic and therapeutic values. In this review, we systematically summarize the role of circRNAs in common bacterial infections and their potential roles as diagnostic markers and therapeutic targets.

Keywords: Bacterial infections; Circular RNAs; Diagnosis; Treatment.

Publication types

  • Review

MeSH terms

  • Bacterial Infections* / genetics
  • Humans
  • RNA, Circular* / genetics

Substances

  • RNA, Circular