Gut microbiota, malnutrition, and immunity: COVID-19's confounding triad

Anna Creus-Cuadros; M Mahebali Tabusi; Valeria Carpio-Arias; B Brett Finlay

doi:10.1016/j.chom.2023.05.020

Gut microbiota, malnutrition, and immunity: COVID-19's confounding triad

Cell Host Microbe. 2023 Jun 14;31(6):851-855. doi: 10.1016/j.chom.2023.05.020.

Authors

Anna Creus-Cuadros¹, M Mahebali Tabusi¹, Valeria Carpio-Arias², B Brett Finlay³

Affiliations

¹ Department of Microbiology and Immunology, University of British Columbia, Vancouver, BC, Canada; Michael Smith Laboratories, University of British Columbia, Vancouver, BC, Canada.
² Research Group on Human Food and Nutrition (GIANH), Escuela Superior Politécnica de Chimborazo, Riobamba, Ecuador.
³ Department of Microbiology and Immunology, University of British Columbia, Vancouver, BC, Canada; Michael Smith Laboratories, University of British Columbia, Vancouver, BC, Canada; Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, BC, Canada. Electronic address: bfinlay@interchange.ubc.ca.

Abstract

The coronavirus disease has swept the world, bringing scientists from multiple disciplines together to work on a focused cause. In this forum, we discuss different roles that microbiota, malnutrition, and immunity have on severity of coronavirus disease and the importance of studying them from a gut-systemic perspective using multi-omics approaches.

MeSH terms

COVID-19*
Gastrointestinal Microbiome*
Humans
Malnutrition* / complications
Microbiota*