Effect of PCSK9 Inhibition on the Plasma Proteome: A SPIRE SubStudy

Affiliations

• ¹ Department of Vascular Medicine, Amsterdam University Medical Centers, University of Amsterdam, The Netherlands (J.M.K., G.K.H., E.S.G.S., N.S.N.).
• ² Department of Cardiology, Radboud University Medical Centre, Nijmegen, the Netherlands (T.S.J.O., J.H.C.).
• ³ Department of Cardiology, Northwest Clinics, Alkmaar, the Netherlands (T.S.J.O., J.H.C.).
• ⁴ Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, United Kingdom (D.G.).
• ⁵ Department of Pharmacological and Biomolecular Sciences, University of Milan, Milano, Italy (A.L.C.).
• ⁶ IRCCS Multimedica, Milano, Italy (A.L.C.).
• ⁷ Deutsches Herzzentrum München, Technische Universität München, Munich, Germany (W.K.).
• ⁸ German Centre for Cardiovascular Research (DZHK e.V.), partner site Munich Heart Alliance, Germany (W.K).
• ⁹ Institute of Epidemiology and Medical Biometry, University of Ulm, Germany (W.K.).
• ¹⁰ Divisions of Preventive Medicine and Cardiovascular Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA (P.M.R.).
• ¹¹ Department of Cardiology, Amsterdam University Medical Centers, Vrije Universiteit Amsterdam, The Netherlands (N.S.N.).