The novel HLA-B*51:381 allele, identified in a Chinese individual through Sanger dideoxy nucleotide sequencing

HLA. 2023 Sep;102(3):365-366. doi: 10.1111/tan.15130. Epub 2023 Jun 14.

Hang Lei^{1

2}, Chuan-He Jiang³, Ke-Ming Du⁴, Zhong-Zheng Zheng⁴, Xiao-Hong Cai^{1

2}

¹ Department of Laboratory Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
² Blood Transfusion Department, Ruijin Hospital, Medical School of Shanghai Jiao Tong University, Shanghai, China.
³ Shanghai Institute of Hematology, National Research Center for Translational Medicine at Shanghai, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
⁴ Shanghai Tissuebank Biotechnology Co., Ltd, Shanghai, China.

Abstract

HLA-B*51:381 differs from HLA-B*51:01:01:01 by one nucleotide in exon 5.

Keywords: HLA-B*51:381; novel allele; sequencing-based typing.