Neural mechanisms of comforting: Prosocial touch and stress buffering

Abstract

Comforting is a crucial form of prosocial behavior that is important for maintaining social unity and improving the physical and emotional well-being of social species. It is often expressed through affiliative social touch toward someone in distress, providing relief for their distressed state. In the face of increasing global distress, these actions are paramount to the continued improvement of individual welfare and the collective good. Understanding the neural mechanisms responsible for promoting actions focused on benefitting others is particularly important and timely. Here, we review prosocial comforting behavior, emphasizing synthesizing recent studies carried out using rodent models. We discuss its underlying behavioral expression and motivations, and then explore both the neurobiology of prosocial comforting in a helper animal and the neurobiology of stress relief following social touch in a recipient as part of a feedback loop interaction.

Keywords: ACC; Affiliative behavior; Allogrooming; Altruism; Amygdala; Buffering; Comforting; Emotional state; Hierarchy; Mice; Neural circuit; Oxytocin; Prosocial behavior; Rodents; Social; Social touch; Stress.