Knowledge, attitude and practice of healthcare workers towards antibiotic resistance during the COVID-19 pandemic

Hadi Al Sulayyim; Rohani Ismail; Abdullah Al Hamid; Noraini Abdul Ghafar

doi:10.1093/jacamr/dlad068

Knowledge, attitude and practice of healthcare workers towards antibiotic resistance during the COVID-19 pandemic

JAC Antimicrob Resist. 2023 Jun 5;5(3):dlad068. doi: 10.1093/jacamr/dlad068. eCollection 2023 Jun.

Authors

Hadi Al Sulayyim^{1

2}, Rohani Ismail¹, Abdullah Al Hamid², Noraini Abdul Ghafar³

Affiliations

¹ Interdisciplinary Health Unit, School of Health Science, Universiti Sains Malaysia (Health Campus), Kubang Kerian, Kelantan, Malaysia.
² Saudi Ministry of Health, Najran, Saudi Arabia Affiliation.
³ Biomedicine Program, School of Health Science, Universiti Sains Malaysia (Health Campus), Kubang Kerian, Kelantan, Malaysia.

Abstract

Background: During the novel Coronavirus 2019 (COVID-19) outbreak, there was an overuse of antibiotics in hospitals. The improper use of antibiotics during COVID-19 has increased antibiotic resistance (AR), which has been reported in multiple studies.

Objectives: To assess the healthcare workers' (HCWs) knowledge, attitude and practice (KAP) in relation to AR during the era of COVID-19, and identify the associated factors with good knowledge, positive attitude and good practice.

Methods: A cross-sectional design was used to assess the KAP of HCWs in Najran, Kingdom of Saudi Arabia (KSA). A validated questionnaire was used to collect participants' data, which consisted of the following information; socio-demographics, knowledge, attitude and items for practice. Data were presented as percentages and median (IQR). Mann-Whitney and Kruskal Wallis tests were used to compare them. Logistic regression was used to identify the associated factors linked to KAP.

Results: The study included 406 HCWs. Their median (IQR) knowledge score was 72.73% (27.27%-81.82%), attitude score was 71.43% (28.57%-71.43%) and practice score was 50% (0%-66.67%). About 58.1% of the HCWs stated that antibiotics could be used to treat COVID-19 infection; 19.2% of the participants strongly agreed and 20.7% agreed that during the COVID-19 pandemic, antibiotics were overused at their healthcare institutions. Only 18.5% strongly agreed and 15.5% agreed when asked whether antibiotics used properly for the right indication and duration can still result in AR. The significantly associated factors with good knowledge were nationality, cadre and qualification. A positive attitude was significantly associated with age, nationality and qualification. Good practice was significantly associated with age, cadre, qualification and working place.

Conclusion: Although the HCWs had a positive attitude regarding AR during COVID-19, their knowledge and practice need significant improvement. Implementation of effective educational and training programmes are urgently needed. In addition, further prospective and clinical trial studies are needed to better inform these programmes.