Spotlight on Schlemm's Canal MicroStent Injection in Patients with Glaucoma

Clin Ophthalmol. 2023 Jun 2:17:1557-1564. doi: 10.2147/OPTH.S388293. eCollection 2023.

Abstract

Minimally invasive glaucoma surgery (MIGS) has revolutionized glaucoma care with its favorable safety profile and ability to delay or minimize the need for traditional, bleb-based procedures. Microstent device implantation is a type of angle-based MIGS, which reduces intraocular pressure (IOP) through bypass of the juxtacanalicular trabecular meshwork (TM) and facilitation of aqueous outflow into the Schlemm's canal. Although there are limited microstent devices on the market, multiple studies have evaluated the safety and efficacy of iStent® (Glaukos Corp.), iStent Inject® (Glaukos Corp.), and Hydrus® Microstent (Alcon) in the treatment of mild-to-moderate open-angle glaucoma, with and without concurrent phacoemulsification. This review attempts to provide a comprehensive evaluation of injectable angle-based microstent MIGS devices in the treatment of glaucoma.

Keywords: Hydrus microstent; Schlemm’s canal; aqueous outflow; glaucoma; iStent; microstent injection.

Publication types

  • Review

Grants and funding

No funding or grant support was obtained for this study.