Transcriptomics, proteomics, metabolomics and network pharmacology reveal molecular mechanisms of multi-targets effects of Shenxianshengmai improving human iPSC-CMs beating

Affiliations

• ¹ Department of Cardiology, Shanghai Institute of Cardiovascular Diseases, Shanghai Xuhui District Central Hospital & Zhongshan-Xuhui Hospital, Zhongshan Hospital, Fudan University, Shanghai, China.
• ² Department of Medical Examination, Shanghai Xuhui District Central Hospital, Shanghai, China.
• ³ Institute of Clinical Science, Zhongshan Hospital, Fudan University, Shanghai, China.
• ⁴ Center for Bioinformatics and Computational Biology, East China Normal University, Shanghai, China.
• ⁵ Shandong Buchang Pharmaceutical Co., Ltd., Heze, Shandong, China.
• ⁶ Jining Medical University, Jining, China.
• ⁷ Department of Cardiology, Shanghai Eighth People's Hospital, Shanghai, China.