Mipomersen

Excerpt

Mipomersen is a lipid-lowering drug used in the treatment of homozygous familial hypercholesterolemia. It is an antisense oligonucleotide inhibitor of apolipoprotein B-100. This activity reviews the indications, mechanism of action, and contraindications of mipomersen for managing homozygous familial hypercholesterolemia. This activity will cover the indications, potential adverse effects and contraindications, and other critical elements of mipomersen therapy. The role of the interprofessional team in the management of patients with homozygous familial hypercholesterolemia who may benefit from mipomersen is dis.