Mammary Analogue Secretory Carcinoma of Parotid - a Pathological Mystery

Indian J Otolaryngol Head Neck Surg. 2023 Jun;75(2):905-908. doi: 10.1007/s12070-022-03142-w. Epub 2022 Sep 9.

Abstract

Salivary gland neoplasms account for 3-6% of head and neck tumours. 70-80% of parotid tumours are benign in histopathology. FNAC has an overall accuracy of 95% in diagnosis of parotid neoplasms. However, the remaining 5% still pose a histopathological mystery which may require a surgical excision of the parotid. We report a case of a 42 year-old-man with a history of parotid swelling and a FNAC report which showed a possibility of a low-grade mucoepidermoid carcinoma or a ductal adenocarcinoma. Final histopathological diagnosis after surgical excision revealed a new pathological entity in mammary analogue secretory carcinoma of parotid.

Keywords: Immunohistochemistry; Mammary Analogue Secretory Carcinoma; Parotid; Salivary gland.