Chronic Suppurative Otitis Media Patient Presenting With Hyperhomocysteinemia in Granulomatosis With Polyangiitis

Dharam P Bansal; Ram K Jat; Medha Gupta

doi:10.7759/cureus.38412

Chronic Suppurative Otitis Media Patient Presenting With Hyperhomocysteinemia in Granulomatosis With Polyangiitis

Cureus. 2023 May 1;15(5):e38412. doi: 10.7759/cureus.38412. eCollection 2023 May.

Authors

Dharam P Bansal¹, Ram K Jat¹, Medha Gupta¹

Affiliation

¹ General Medicine, Mahatma Gandhi Medical College and Hospital, Jaipur, IND.

Abstract

Granulomatosis with Polyangiitis (GPA) can present with Cerebral Venous Sinus Thrombosis (CVST), Chronic Suppurative Otitis Media, and Lower Motor Neuron (LMN) Facial Palsy. However, an association between CVST and Hyperhomocysteinemia in GPA has not previously been reported. Here, we report a case of CVST and Hyperhomocysteinemia in Proteinase 3 anti-neutrophil cytoplasmic antibody (PR3-ANCA) positive GPA without renal involvement.

Keywords: c-anca; cerebral venous sinus thrombosis; cyclophosphamide; granulomatosis with polyangiitis; hyperhomocysteinemia; hypertrophic pachymeningitis; mthfr; systemic vasculitis; wegner’s granulomatosis.

Publication types

Case Reports