Advances in therapeutic applications of silver nanoparticles

Chem Biol Interact. 2023 Sep 1:382:110590. doi: 10.1016/j.cbi.2023.110590. Epub 2023 Jun 1.

Abstract

Nanotechnology is one of the most appealing area for developing new applications in biotechnology and medicine. For decades, nanoparticles have been extensively studied for a variety of biomedical applications. Silver has evolved into a potent antibacterial agent that can be used in a variety of nanostructured materials of various shapes and sizes. Silver nanoparticles (AgNP) based antimicrobial compounds are employed in a wide range of applications, including medicinal uses, surface treatment and coatings, the chemical and food industries, and agricultural productivity. When designing formulations for specific applications, the size, shape, and surface area of AgNPs are all crucial structural aspects to consider. Different methods for producing AgNPs with varying sizes and forms that are less harmful have been devised. The anticancer, anti-inflammatory, antibacterial, antiviral, and anti-angiogenic properties of AgNPs have been addressed in this review, as well as their generation and processes. Herein, we have reviewed the advances in therapeutic applications of AgNPs, as well as their limitations and barriers for future applications.

Keywords: Antimicrobial effects; Cancer; Nanomaterials; Oxidative stress; Pharmacological effects; Silver nanoparticles.

Publication types

  • Review

MeSH terms

  • Adjuvants, Immunologic / therapeutic use
  • Animals
  • Anti-Inflammatory Agents / therapeutic use
  • Antineoplastic Agents / therapeutic use
  • Biosensing Techniques
  • Humans
  • Hypoglycemic Agents / therapeutic use
  • Metal Nanoparticles* / adverse effects
  • Metal Nanoparticles* / chemistry
  • Metal Nanoparticles* / therapeutic use
  • Silver* / adverse effects
  • Silver* / therapeutic use

Substances

  • Silver
  • Antineoplastic Agents
  • Adjuvants, Immunologic
  • Anti-Inflammatory Agents
  • Hypoglycemic Agents