Urea-based magnetic porous organic frameworks as novel adsorbent for the enrichment of phenylurea herbicides in foods

Jinhua Li; Xiuli Xu; Feng Zhang; Wei Guo; Xiujuan Wang; Yun Xie; Feifang Zhang

doi:10.1016/j.foodchem.2023.136436

Urea-based magnetic porous organic frameworks as novel adsorbent for the enrichment of phenylurea herbicides in foods

Food Chem. 2023 Nov 1:425:136436. doi: 10.1016/j.foodchem.2023.136436. Epub 2023 May 22.

Authors

Jinhua Li¹, Xiuli Xu², Feng Zhang³, Wei Guo², Xiujuan Wang², Yun Xie², Feifang Zhang⁴

Affiliations

¹ Institute of Food Safety, Chinese Academy of Inspection and Quarantine, Beijing 100176, China; School of Pharmacy, East China University of Science and Technology, Shanghai 200237, China; Key Laboratory of Food Quality and Safety for State Market Regulation, Beijing 100176, China.
² Institute of Food Safety, Chinese Academy of Inspection and Quarantine, Beijing 100176, China; Key Laboratory of Food Quality and Safety for State Market Regulation, Beijing 100176, China.
³ Institute of Food Safety, Chinese Academy of Inspection and Quarantine, Beijing 100176, China; Key Laboratory of Food Quality and Safety for State Market Regulation, Beijing 100176, China. Electronic address: fengzhang@126.com.
⁴ School of Pharmacy, East China University of Science and Technology, Shanghai 200237, China. Electronic address: zhangff@ecust.edu.cn.

PMID: 37267786
DOI: 10.1016/j.foodchem.2023.136436

Abstract

A novel urea-based magnetic porous organic frameworks Fe₃O₄@UPOFs (ETTA-PPDI) was synthesized by a simple polymerization reaction under mild conditions. The adsorbent displayed desirable adsorption performance for phenylurea herbicides (PUHs) with optimized adsorption time of only 4 min. The adsorption capacities of the adsorbent for PUHs ranged from 47.30 to 111.93 mg g^-1. A magnetic solid-phase extraction based on Fe₃O₄@UPOFs combined with high performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) was established for the efficient determination of six PUHs in food samples (wheat, edible oil and cucumber), with determination coefficient (R²) ≥ 0.9972. The LODs of the method were in the range of 0.003-0.07 μg kg^-1 and recoveries ranged from 82.00 to 112.53%. The relative standard deviations were lower than 6.7%. The newly prepared adsorbent displayed great application prospects for the efficient enrichment of trace phenylurea herbicides in complex food matrices.

Keywords: Food samples; HPLC-MS/MS; Magnetic solid-phase extraction; Phenylurea herbicides; Urea-functionalized magnetic porous organic frameworks.

MeSH terms

Adsorption
Chromatography, High Pressure Liquid / methods
Herbicides* / analysis
Magnetic Phenomena
Porosity
Solid Phase Extraction / methods
Tandem Mass Spectrometry
Urea*

Substances

Urea
Herbicides