Joy in medicine, or the loss of it, is a popular topic of conversation, even more so since the pandemic. Burnout in oncology is common and diminishes the satisfaction of practicing medicine. One of the challenges clinicians face is the way in which modern clinical practice takes us away from what we find most meaningful in our work: time with patients. Strategies like being kind, expressing gratitude, and using effective communication skills can establish more connection with our colleagues and our patients, and, in turn, result in a more joyful work environment. Creating space for more moments of feeling deep interconnectedness with patients and colleagues can rekindle feelings of joy in oncology practice. This article reviews the concepts of joy in medicine, the term sacred moments, and outlines practical strategies and communication skills that are effective in enhancing the patient-provider relationship.