Diabetic Kidney Disease: An Update

Sonali Gupta; Mary Dominguez; Ladan Golestaneh

doi:10.1016/j.mcna.2023.03.004

Diabetic Kidney Disease: An Update

Med Clin North Am. 2023 Jul;107(4):689-705. doi: 10.1016/j.mcna.2023.03.004. Epub 2023 Apr 7.

Authors

Sonali Gupta¹, Mary Dominguez², Ladan Golestaneh²

Affiliations

¹ Department of Medicine, Division of Nephrology, Albert Einstein College of Medicine, 3411 Wayne Avenue, 5th Floor, Bronx, NY 10467, USA. Electronic address: sogupta@montefiore.org.
² Department of Medicine, Division of Nephrology, Albert Einstein College of Medicine, 3411 Wayne Avenue, 5th Floor, Bronx, NY 10467, USA.

PMID: 37258007
DOI: 10.1016/j.mcna.2023.03.004

Abstract

Diabetes is a major public health challenge and diabetic kidney disease (DKD), a broader diagnostic term than diabetic nephropathy, is the leading cause of chronic kidney disease and end-stage kidney disease in the United States and worldwide. A better understanding of the underlying pathophysiological mechanisms of DKD, and recent clinical trials testing new therapeutic interventions, have shown promising results to curb this epidemic. Given the global health burden of DKD, it is extremely important to prioritize prevention, early recognition, referral, and aggressive management of DKD in the primary care setting.

Keywords: Albuminuria; Chronic kidney disease; Diabetic kidney disease; Diabetic nephropathy; End-stage kidney disease; Proteinuria.

Publication types

Review

MeSH terms

Diabetes Mellitus, Type 2*
Diabetic Nephropathies* / diagnosis
Diabetic Nephropathies* / epidemiology
Diabetic Nephropathies* / therapy
Humans
Kidney Failure, Chronic* / epidemiology
Kidney Failure, Chronic* / prevention & control
Renal Insufficiency, Chronic* / diagnosis
Renal Insufficiency, Chronic* / epidemiology
Renal Insufficiency, Chronic* / etiology