How therapeutic advances have transformed the medical landscape: a primer for clinicians

Narcyz Ghinea; Wendy Lipworth; Ian Kerridge; John R Zalcberg

doi:10.1111/imj.16142

How therapeutic advances have transformed the medical landscape: a primer for clinicians

Intern Med J. 2023 Aug;53(8):1306-1310. doi: 10.1111/imj.16142. Epub 2023 Jun 23.

Authors

Narcyz Ghinea¹, Wendy Lipworth¹, Ian Kerridge^{1

2

3}, John R Zalcberg⁴

Affiliations

¹ Department of Philosophy, Macquarie University, Sydney, New South Wales, Australia.
² Sydney Health Ethics, School of Public Health, Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia.
³ Department of Haematology, Royal North Shore Hospital, Sydney, New South Wales, Australia.
⁴ Department of Medical Oncology, Alfred Health and School of Public Health, Monash University, Melbourne, Victoria, Australia.

PMID: 37255280
DOI: 10.1111/imj.16142

Abstract

Novel medicines are entering the market rapidly and are increasingly being used alone or in combination to treat illnesses of every sort. While transforming the lives of many patients, these new therapies have also forced us to reconsider the way we evaluate, use and fund medicines. This article offers a primer to help practitioners understand how the therapeutic landscape is changing and how this might impact the evidence generation, access to interventions, patient experience and quality of care.

Keywords: clinical practice; clinical research; drug development; funding; pharmaceuticals; reimbursement.

Publication types

Review