Development of the Commercial Manufacturing Process for Nirmatrelvir in 17 Months

ACS Cent Sci. 2023 Mar 29;9(5):849-857. doi: 10.1021/acscentsci.3c00145. eCollection 2023 May 24.

Abstract

The advancement of nirmatrelvir, the active ingredient in Paxlovid, from discovery to emergency use authorization was achieved in just 17 months, requiring an unprecedented rate of chemical process development.

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  • News