Design and development of second-generation fabric phase sorptive extraction membranes: Proof-of-concept for the extraction of organophosphorus pesticides from apple juice prior to GC-MS analysis

Natalia Manousi; Antonio Ferracane; Natasa P Kalogiouri; Abuzar Kabir; Kenneth G Furton; Peter Q Tranchida; George A Zachariadis; Luigi Mondello; Victoria F Samanidou; Erwin Rosenberg

doi:10.1016/j.foodchem.2023.136423

Design and development of second-generation fabric phase sorptive extraction membranes: Proof-of-concept for the extraction of organophosphorus pesticides from apple juice prior to GC-MS analysis

Food Chem. 2023 Oct 30:424:136423. doi: 10.1016/j.foodchem.2023.136423. Epub 2023 May 20.

Affiliations

¹ Laboratory of Analytical Chemistry, Department of Chemistry, Aristotle University of Thessaloniki, Thessaloniki 54124, Greece; Laboratory of Pharmaceutical Analysis, School of Pharmacy, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece. Electronic address: nmanousi@chem.auth.gr.
² Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Messina, Italy.
³ Laboratory of Analytical Chemistry, Department of Chemistry, Aristotle University of Thessaloniki, Thessaloniki 54124, Greece.
⁴ International Forensic Research Institute, Department of Chemistry and Biochemistry, Florida International University, Miami, FL, USA. Electronic address: akabir@fiu.edu.
⁵ International Forensic Research Institute, Department of Chemistry and Biochemistry, Florida International University, Miami, FL, USA.
⁶ Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Messina, Italy; Chromaleont s.r.l., c/o Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Messina, Italy.
⁷ Institute of Chemical Technologies and Analytics, Vienna University of Technology, 1060 Vienna, Austria.

PMID: 37247598
DOI: 10.1016/j.foodchem.2023.136423

Abstract

In this work, different sol-gel sorbent-coated second-generation fabric phase sorptive extraction (FPSE) membranes were synthesized using titania-based sol-gel precursors. The proposed membranes were tested for their efficiency to extract eleven selected organophosphorus pesticides (OPPs) from apple juice samples. Among the examined materials, sol-gel C₁₈ coated titania-based FPSE membranes showed the highest extraction efficiency. These membranes were used for the optimization and validation of an FPSE method prior to analysis by gas chromatography-mass spectrometry. The detection limits for OPPs ranged between 0.03 and 0.08 ng mL^-1. Moreover, the relative standard deviation was < 8.2% and 8.4% for intra-day and inter-day studies, respectively. The relative recoveries were 91-110% (intra-day study) and 90-106% (inter-day study) for all the target analytes, demonstrating good overall method accuracy. Moreover, the novel membranes were reusable at least 5 times. The titania-based membranes were compared to the conventional silica-based membranes and their utilization resulted in higher extraction recoveries.

Keywords: Apple juice; Fabric phase sorptive extraction; Gas chromatography-mass spectrometry; Organophosphorus pesticides; Titanium oxide.

MeSH terms

Gas Chromatography-Mass Spectrometry / methods
Malus*
Organophosphorus Compounds / analysis
Pesticides* / analysis

Substances

Pesticides
titanium dioxide
Organophosphorus Compounds