Detection and Phylogenetic Characterization of a Novel Adenovirus Found in Lesser Mouse-Eared Bat (Myotis blythii) in South Kazakhstan

Kobey Karamendin; Aidyn Kydyrmanov; Temirlan Sabyrzhan; Sardor Nuralibekov; Yermukhammet Kasymbekov; Yelizaveta Khan

doi:10.3390/v15051139

Detection and Phylogenetic Characterization of a Novel Adenovirus Found in Lesser Mouse-Eared Bat (Myotis blythii) in South Kazakhstan

Viruses. 2023 May 10;15(5):1139. doi: 10.3390/v15051139.

Authors

Kobey Karamendin¹, Aidyn Kydyrmanov¹, Temirlan Sabyrzhan¹, Sardor Nuralibekov¹, Yermukhammet Kasymbekov¹, Yelizaveta Khan¹

Affiliation

¹ Scientific Production Center of Microbiology and Virology, 105 Bogenbay Batyr Str., Almaty A25K1G0, Kazakhstan.

Abstract

Bats are an important natural reservoir of various pathogenic microorganisms, and regular monitoring is necessary to track the situation of zoonotic infections. When examining samples from bats in South Kazakhstan, nucleotide sequences of putative novel bat adenovirus (AdV) species were found. Estimates of amino acid identities of the hexon protein have shown that potentially novel Bat mastadenovirus BatAdV-KZ01 shared higher similarity with monkey Rhesus adenovirus 59 (74.29%) than with Bat AdVs E and H (74.00%). Phylogenetically, BatAdV-KZ01 formed a separate clade, distant from Bat AdVs and other mammalian AdVs. Since adenoviruses are essential pathogens for many mammals, including humans and bats, this finding is of interest from both scientific and epidemiological points of view.

Keywords: Kazakhstan; Myotis blythii; bat; mastadenovirus; transmission.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Adenoviridae / genetics
Adenoviridae Infections* / veterinary
Animals
Chiroptera*
Humans
Kazakhstan
Mastadenovirus*
Phylogeny

Grants and funding

This work was supported by a grant № AP14869099 from the Ministry of Education and Science of the Republic of Kazakhstan.