The Role of Vitamins in the Pathogenesis of Asthma

Int J Mol Sci. 2023 May 10;24(10):8574. doi: 10.3390/ijms24108574.

Abstract

Vitamins play a crucial role in the proper functioning of organisms. Disturbances of their levels, seen as deficiency or excess, enhance the development of various diseases, including those of the cardiovascular, immune, or respiratory systems. The present paper aims to summarize the role of vitamins in one of the most common diseases of the respiratory system, asthma. This narrative review describes the influence of vitamins on asthma and its main symptoms such as bronchial hyperreactivity, airway inflammation, oxidative stress, and airway remodeling, as well as the correlation between vitamin intake and levels and the risk of asthma in both pre- and postnatal life.

Keywords: airway hyperreactivity; airway inflammation; airway remodeling; asthma; maternal intake; oxidative stress; pregnancy; risk of developing asthma; vitamins.

Publication types

  • Review

MeSH terms

  • Asthma* / diagnosis
  • Asthma* / etiology
  • Bronchial Hyperreactivity*
  • Humans
  • Vitamin A
  • Vitamin K
  • Vitamins / therapeutic use

Substances

  • Vitamins
  • Vitamin A
  • Vitamin K

Grants and funding

This research received no external funding.