Distribution and Characteristics of Ocular Biometric Parameters among a Chinese Population: A Hospital-Based Study

Ophthalmol Ther. 2023 Aug;12(4):2117-2131. doi: 10.1007/s40123-023-00716-x. Epub 2023 May 26.

Abstract

Introduction: This study aimed to describe the distribution and characteristics of ocular biometric parameters among a large Chinese population.

Methods: This retrospective cross-sectional study included 146,748 subjects whose ocular biometric parameters were measured at the ophthalmology clinic of West China Hospital, Sichuan University, and recorded in the hospital database. Ocular biometric parameters, including axial length, anterior chamber depth, corneal keratometry, and keratometric astigmatism, were recorded. Only monocular data for each subject were analyzed to avoid bias.

Results: Valid data from 85,770 subjects (43,552 females and 42,218 males) aged 3-114 years were included in this study. The mean axial length, mean anterior chamber depth, average corneal keratometry, and mean keratometric astigmatism were 24.61 mm, 3.30 mm, 43.76 D, and 1.19 D, respectively. The stratification of the ocular parameters by age and gender showed significant inter-gender and inter-age differences.

Conclusions: Analysis of a large population of subjects in western China aged 3-114 years showed that the distribution and characteristics of ocular biometric parameters, including axial length, anterior chamber depth, corneal keratometry, and keratometric astigmatism, differed by age and gender. This study is the first to describe ocular biometric parameters in subjects aged > 100 years.

Keywords: Adolescents; Anterior chamber depth; Axial length; Corneal keratometry; Gender; Ocular biometric parameters; Older generation.