Diagnosis and Treatment of Rare Adult Embryonal Rhabdomyosarcoma in Maxillary Sinus

J Craniofac Surg. 2023 Jul-Aug;34(5):e505-e507. doi: 10.1097/SCS.0000000000009378. Epub 2023 May 25.

Abstract

Objective: To investigate the clinicopathological features, imaging features, diagnosis, and prognosis of embryonal rhabdomyosarcoma (ERMS) in the maxillary sinus.

Methods: The detailed clinical data of rare patients with embryonal ERMS of maxillary sinus admitted to our hospital were retrospectively analyzed, and the embryonal ERMS was confirmed by pathological examination and immunohistochemistry, and the relevant literature was reviewed.

Results: A 58-year-old man was admitted to the hospital with the chief complaint of "numbness and swelling of the left cheek for 1 and a half months". Blood routine, biochemistry, paranasal sinus computed tomography, and magnetic resonance imaging were performed after admission, and the pathology showed ERMS. At present, it is generally in good condition. Pathological examination showed that the cells were all small and round. Immunohistochemistry showed Desmin (+) and Ki-67 (+70%).

Conclusion: The early symptoms of ERMS of the maxillary sinus are atypical and diverse, with a high degree of malignancy, rapid progression, strong invasiveness, and poor prognosis. Early diagnosis and treatment should be based on clinical characteristics, imaging examination, and immunohistochemical results.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Cheek / pathology
  • Humans
  • Immunohistochemistry
  • Male
  • Maxillary Sinus / diagnostic imaging
  • Maxillary Sinus / pathology
  • Maxillary Sinus / surgery
  • Middle Aged
  • Retrospective Studies
  • Rhabdomyosarcoma* / pathology
  • Rhabdomyosarcoma, Embryonal* / diagnostic imaging
  • Rhabdomyosarcoma, Embryonal* / surgery