Hox genes encode a family of conserved transcription factors that play important roles in specifying regions of the body plan along the anterior-posterior axis. A new paper in Development introduces new approaches and provides further insights into the transcriptional mechanisms controlling Hox gene expression during vertebrate development. To hear more about the story behind the paper, we caught up with the first author Zainab Afzal and her PhD supervisor Robb Krumlauf, Professor at the Stowers Institute for Medical Research.
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