1 Federal Institute for Drugs and Medical Devices, Federal Opium Agency, Bonn, Germany; Department of Medicine and Health Services Research, Barmer Health Insurance, Wuppertal, Germany; Pain Clinic, Department of Anesthesiology, University Medical Center Göttingen, Göttingen, Germany; Internal Medicine 1, Saarbrücken University Hospital, and Department for Psychosomatic Medicine and Psychotherapy, Technical University of Munich whaeuser@klinikum-saarbruecken.de.