Clinical Results, Risk Factors, and Future Directions of Ultrasound-Guided Percutaneous Microwave Ablation for Hepatocellular Carcinoma

Tian-Tian Dong; Lan Wang; Ming Li; Ci Yin; Yuan-Yuan Li; Fang Nie

doi:10.2147/JHC.S409011

Clinical Results, Risk Factors, and Future Directions of Ultrasound-Guided Percutaneous Microwave Ablation for Hepatocellular Carcinoma

J Hepatocell Carcinoma. 2023 May 15:10:733-743. doi: 10.2147/JHC.S409011. eCollection 2023.

Authors

Tian-Tian Dong^{1

2

3}, Lan Wang^{1

2

3}, Ming Li^{1

2

3}, Ci Yin^{1

2

3}, Yuan-Yuan Li^{1

2

3}, Fang Nie^{1

2

3}

Affiliations

¹ Ultrasound Medical Center, Lanzhou University Second Hospital, Lanzhou, 730030, People's Republic of China.
² Ultrasound Center, Gansu Province Clinical Research Center for Ultrasound, Lanzhou, 730030, People's Republic of China.
³ Intelligence Ultrasound Center, Gansu Province Medical Engineering Research Center for Intelligence Ultrasound, Lanzhou, 730030, People's Republic of China.

Abstract

Hepatocellular carcinoma (HCC) is one of the most common malignancies worldwide, with a relatively poor prognosis, especially for advanced HCC. With the availability of a variety of treatment options, the treatment strategies for HCC have become more and more diversified. Microwave ablation (MWA) has gradually been considered as a viable alternative to surgical resection (SR) owing to its comparable long-term survival, reduced complications, and greater preservation of hepatic parenchyma. However, clinical outcomes, tumor progression, and recurrence of HCC after MWA remain major concerns. Here, after reviewing the current therapeutic options for HCC, we focus on MWA, describing the advantages and challenges of MWA and the clinical results after treatment. We then focused on prognostic factors that influence post-ablation clinical outcomes and briefly presented the strategy of MWA for future clinical treatment.

Keywords: clinical outcomes; hepatocellular carcinoma; microwave ablation; progression.

Publication types

Review

Grants and funding

This work was supported by the Key Research and Development Project of Gansu Province, China [grant number 21YF5FA122]; The Youth Science and Technology Fund program of Gansu Province, China [grant numbers 22JR11RA074].