Isolation and genetic characterization of a mammalian orthoreovirus from Vespertilio sinensis in Japan

Arch Virol. 2023 May 20;168(6):165. doi: 10.1007/s00705-023-05782-x.

Abstract

Throughout East Asia, Europe, and North America, mammalian orthoreovirus (MRV), for which bats have been proposed to be natural reservoirs, has been detected in a variety of domestic and wild mammals, as well as in humans. Here, we isolated a novel MRV strain (designated as Kj22-33) from a fecal sample from Vespertilio sinensis bats in Japan. Strain Kj22-33 has a 10-segmented genome with a total length of 23,580 base pairs. Phylogenetic analysis indicated that Kj22-33 is a serotype 2 strain, the segmented genome of which has undergone reassortment with that of other MRV strains.

MeSH terms

  • Animals
  • Chiroptera*
  • Europe
  • Genome, Viral
  • Humans
  • Japan
  • Orthoreovirus* / genetics
  • Orthoreovirus, Mammalian*
  • Phylogeny
  • Reoviridae Infections*