Stereotactic Radiosurgery for Intracranial Meningiomas

Stylianos Pikis; Georgios Mantziaris; Chloe Dumot; Zhiyuan Xu; Jason Sheehan

doi:10.1016/j.nec.2023.02.010

Stereotactic Radiosurgery for Intracranial Meningiomas

Neurosurg Clin N Am. 2023 Jul;34(3):455-462. doi: 10.1016/j.nec.2023.02.010. Epub 2023 Apr 7.

Authors

Stylianos Pikis¹, Georgios Mantziaris¹, Chloe Dumot¹, Zhiyuan Xu¹, Jason Sheehan²

Affiliations

¹ Department of Neurological Surgery, University of Virginia Health System, Charlottesville, VA 22908, USA.
² Department of Neurological Surgery, University of Virginia Health System, Charlottesville, VA 22908, USA. Electronic address: jsheehan@virginia.edu.

PMID: 37210134
DOI: 10.1016/j.nec.2023.02.010

Abstract

Meningiomas are thought to originate from the meningothelial cells of the arachnoid mater and are the most common primary brain tumor in adults. Histologically confirmed meningiomas occur with an incidence of 9.12/100,000 population and account for 39% of all primary brain tumors and 54.5% of all non-malignant brain tumors. Risk factors for meningioma include age 65 years and older, female gender, African-American race, history of exposure to head and neck ionizing radiation, and certain genetic disorders such as neurofibromatosis II. Intracranial meningiomas are the most commonly benign, WHO Grade I neoplasms. Atypical and anaplastic are considered malignant lesions.

Keywords: Complications; Meningioma; Outcomes; Radiosurgery.

Publication types

Review

MeSH terms

Adult
Aged
Brain Neoplasms* / radiotherapy
Brain Neoplasms* / surgery
Female
Humans
Incidence
Meningeal Neoplasms* / radiotherapy
Meningeal Neoplasms* / surgery
Meningioma* / radiotherapy
Meningioma* / surgery
Radiosurgery* / adverse effects
Treatment Outcome