Transplant Onconephrology: An Update

Semin Nephrol. 2022 Nov;42(6):151348. doi: 10.1016/j.semnephrol.2023.151348. Epub 2023 May 18.

Abstract

Transplant onconephrology is a growing specialty focused on the health care of kidney transplant recipients with cancer. Given the complexities associated with the care of transplant patients, along with the advent of novel cancer therapies such as immune checkpoint inhibitors and chimeric antigen-receptor T cells, there is a dire need for the subspecialty of transplant onconephrology. The management of cancer in the setting of kidney transplantation is best accomplished by a multidisciplinary team, including transplant nephrologists, oncologists, and patients. This review addresses the current state and future opportunities for transplant onconephrology, including the roles of the multidisciplinary team, and related scientific and clinical knowledge.

Keywords: Transplant onconephrology; cancer; chimeric antigen–receptor T cell; immune checkpoint inhibitor; immunosuppression; immunotherapy; kidney transplant.

Publication types

  • Review
  • Research Support, N.I.H., Extramural

MeSH terms

  • Humans
  • Kidney Transplantation*
  • Neoplasms* / therapy
  • Nephrologists
  • Transplant Recipients