Identifying the structures of individual RNA isoforms inside cells

Julia C Kenyon; Johnson Mak

doi:10.1038/s41592-023-01904-0

Identifying the structures of individual RNA isoforms inside cells

Nat Methods. 2023 Jun;20(6):791-792. doi: 10.1038/s41592-023-01904-0.

Authors

Julia C Kenyon¹, Johnson Mak²

Affiliations

¹ Department of Pathology, Division of Virology, University of Cambridge, Addenbrookes Hospital, Cambridge, UK. jck33@cam.ac.uk.
² Institute for Glycomics, Griffith University, Gold Coast, Queensland, Australia. j.mak@griffith.edu.au.

Abstract

Nano-DMS-MaP focuses in on the structures of individual RNA isoforms, enabling direct examination of the structural diversity of different RNAs inside cells.

MeSH terms

Protein Isoforms
RNA Isoforms* / chemistry
RNA Isoforms* / genetics

Substances

RNA Isoforms
Protein Isoforms

Grants and funding

R21 AI172534/AI/NIAID NIH HHS/United States