In Los Angeles, California, USA, persistent, refractory shigellosis was diagnosed in an immunocompetent man who has sex with men. Whole-genome sequencing augmented phenotypic antimicrobial susceptibility testing to comprehensively profile bacterial drug resistance and appropriately guide therapy and clear the infection.
Keywords: California; NGS; Shigella; United States; WGS; XDR; bacteria; extensively drug resistant; next-generation sequencing; whole-genome sequencing.