Liver disorders and celiac disease

Rev Esp Enferm Dig. 2024 Jan;116(1):41-42. doi: 10.17235/reed.2023.9516/2023.

Abstract

Celiac disease (CD) is a chronic autoimmune enteropathy triggered by gluten intake. Celiac hepatitis is the most common hepatic manifestation of CD, it usually responds to a gluten-free diet (GFD) and is sometimes the only manifestation in paucisymptomatic CD. Through this descriptive observational study, we determined the prevalence of liver abnormalities upon diagnosis of CD. A total of 140 patients were included. The prevalence of alterations in liver markers at diagnosis of CD was 47%. In 2.9% of patients, liver abnormalities were the only manifestation at diagnosis. A higher prevalence of liver alterations was found in those patients who presented a more severe histological alteration (MARSH 3c).

Publication types

  • Observational Study

MeSH terms

  • Biopsy
  • Celiac Disease* / complications
  • Celiac Disease* / diagnosis
  • Celiac Disease* / epidemiology
  • Diet, Gluten-Free
  • Humans
  • Inflammatory Bowel Diseases*
  • Liver Diseases* / epidemiology
  • Liver Diseases* / etiology