Genomics has significantly impacted the field of medicine, with advances in DNA sequencing leading to personalized medicine and a deeper understanding of the genomic basis of various diseases. The ability to share genomic data is crucial for advancing this field and developing new approaches to understanding the genome. However, the sensitive nature of this data requires secure methods for protecting it during storage and transfer. In this paper, we present a new tool for the secure encryption and decryption of FASTA files without sharing a common secret and with a reduced number of shared keys between the pairs. Our proposal combines symmetric and asymmetric encryption techniques, including the AES (Advanced Encryption Standard) cypher and RSA (Rivest-Shamir-Adleman). The tool is fast, reliable, and secure, outperforming existing tools in terms of security and ease of use. This makes it a valuable solution for the secure sharing and use of sensitive genomic data, representing a significant advancement in the field of genomics.
Keywords: DNA sequencing; FASTA files; Genomics; data security; decryption; encryption.