HTNpedia: A Knowledge Base for Hypertension Research

Lakshmanan Loganathan; Jeyaraman Jeyakanthan; Karthikeyan Muthusamy

doi:10.2174/1386207326666230518162439

HTNpedia: A Knowledge Base for Hypertension Research

Comb Chem High Throughput Screen. 2023 May 18. doi: 10.2174/1386207326666230518162439. Online ahead of print.

Authors

Lakshmanan Loganathan¹, Jeyaraman Jeyakanthan¹, Karthikeyan Muthusamy¹

Affiliation

¹ Department of Bioinformatics, Alagappa University, Karaikudi-630003, Tamil Nadu, India.

PMID: 37202885
DOI: 10.2174/1386207326666230518162439

Abstract

Background: Hypertension is notably a serious public health concern due to its high prevalence and strong association with cardiovascular disease and renal failure. It is reported to be the fourth leading disease that leads to death worldwide.

Objective: Currently, there is no active operational knowledge base or database for hypertension or cardiovascular illness.

Method: The primary data source was retrieved from the research outputs obtained from our laboratory team working on hypertension research. We have presented a preliminary dataset and external links to the public repository for detailed analysis to readers.

Result: As a result, HTNpedia was created to provide information regarding hypertension-related proteins and genes.

Conclusion: The complete webpage is accessible via www.mkarthikeyan.bioinfoau.org/HTNpedia.

Keywords: Drugs; Genes; Hypertension; Knowledgebase; Protein; SNPs.