A strange case of Transthyretin Cardiac Amyloidosis in the Elderly: a diagnostic challenge

Clin Ter. 2023 May-Jun;174(3):235-239. doi: 10.7417/CT.2023.2526.

Abstract

Transthyretin (TTR)-related cardiac amyloidosis is a progressive infiltrative cardiomyopathy that mimics hypertensive, hypertrophic heart disease and may go undiagnosed. We here report the case of a 83-year-old woman, which has rapresented an unique case of transthyretin-related cardiac amyloidosis, as a patient with an initial diagnosis of hypertensive heart disease later develops an infiltrative cardiomyopathy due to amyloid deposits.

Keywords: ATTR; cardiac amyloidosis; heart failure; infiltrative cardiomyopathy; longitudinal strain; transthyretin.

Publication types

  • Case Reports

MeSH terms

  • Aged, 80 and over
  • Amyloidosis* / complications
  • Amyloidosis* / diagnosis
  • Cardiomyopathies* / diagnosis
  • Cardiomyopathies* / etiology
  • Female
  • Heart Diseases*
  • Humans
  • Hypertension*
  • Prealbumin

Substances

  • Prealbumin