Models are essential to further our understanding of lung development and regeneration and to facilitate identification and testing of potential treatments for lung diseases. A wide variety of rodent and human models are available that recapitulate one or more stages of lung development. This chapter describes the existing 'simple' in vitro, in silico and ex vivo models of lung development. We define which stage(s) of development each model recapitulates and highlight their pros and cons.
Keywords: Embryonic; Ex vivo model; In utero; Lung development.
© 2023. The Author(s), under exclusive license to Springer Nature Switzerland AG.