Association of Severe Hypercholesterolemia and Familial Hypercholesterolemia Genotype With Risk of Coronary Heart Disease

Affiliations

• ¹ Division of General Medicine, Columbia University, New York, NY (Y.Z., B.K.B., P.P.B., E.C.O., A.E.M.).
• ² Cardiovascular Disease Initiative, Broad Institute of MIT and Harvard, Cambridge, MA (J.S.D., A.V.K., P.N.).
• ³ Center for Genomic Medicine (J.S.D., A.V.K.), Massachusetts General Hospital, Boston.
• ⁴ Departments of Medicine (A.V.K., P.N., D.S.K.), Harvard Medical School, Boston, MA.
• ⁵ Department of Population Health Science and Policy, Icahn School of Medicine, Mount Sinai, New York, NY (J.L.).
• ⁶ Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA (S.S.A., M.S.L.).
• ⁷ Laboratory for Molecular Medicine, Personalized Medicine, Mass General Brigham, Cambridge, MA (S.S.A., M.S.L., A.N.).
• ⁸ Department of Biostatistics, Boston University School of Public Health, MA (G.M.P.).
• ⁹ Department of Medicine (P.N.), Massachusetts General Hospital, Boston.
• ¹⁰ Institute for Translational Genomics and Population Sciences, Department of Pediatrics, Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA (J.I.R., X.G.).
• ¹¹ Departments of Internal Medicine, Human Genetics, and Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor (C.W.).
• ¹² Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health (E.B.), University of Texas Health Science Center at Houston.
• ¹³ Department of Medicine, Baylor College of Medicine, Houston, TX (C.M.B.).
• ¹⁴ Division of Epidemiology & Community Health, School of Public Health, University of Minnesota, Minneapolis (P.L.L.).
• ¹⁵ Brown Foundation Institute of Molecular Medicine (M.F.), University of Texas Health Science Center at Houston.
• ¹⁶ Northwestern University, Chicago, IL (D.M.L.-J., L.H.).
• ¹⁷ Cardiovascular Health Research Unit, Department of Medicine (B.M.P., J.C.B., J.S.F.), University of Washington, Seattle.
• ¹⁸ Epidemiology (B.M.P., J.S.F.), University of Washington, Seattle.
• ¹⁹ Health Systems and Population Health (B.M.P.), University of Washington, Seattle.
• ²⁰ The Framingham Heart Study, MA (R.S.V.).
• ²¹ Sections of Preventive Medicine and Epidemiology and Cardiology, Department of Medicine, and Department of Epidemiology, Boston University Schools of Medicine and Public Health, and Center for Computing and Data Sciences, Boston University, MA (R.S.V.).
• ²² Department of Neurology, Boston University Chobanian & Avedisian School of Medicine, MA (N.L.H.-C.).
• ²³ Department of Medicine, University of Mississippi Medical Center, Jackson (A.P.C., M.E.H.).
• ²⁴ Center for Public Health Genomics, University of Virginia, Charlottesville (S.S.R.).
• ²⁵ Richard A. and Susan F. Smith Center for Outcomes Research, Beth Israel Deaconess Medical Center, Boston, MA (D.S.K.).
• ²⁶ Pediatrics (S.D.d.F.), Harvard Medical School, Boston, MA.
• ²⁷ Department of Cardiology, Boston Children's Hospital, MA (S.D.d.F.).