Morphology and cell biology - two sides of the same coin: Importance of morphology in choosing Cre experimental models for targeting osteoblasts vs osteocytes

Carla Palumbo; Marzia Ferretti

doi:10.1016/j.bone.2023.116790

Morphology and cell biology - two sides of the same coin: Importance of morphology in choosing Cre experimental models for targeting osteoblasts vs osteocytes

Bone. 2023 Aug:173:116790. doi: 10.1016/j.bone.2023.116790. Epub 2023 May 12.

Authors

Carla Palumbo¹, Marzia Ferretti²

Affiliations

¹ Section of Human Morphology, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Anatomical Institutes, Via del Pozzo 71, 41124 Modena, Italy. Electronic address: carla.palumbo@unimore.it.
² Section of Human Morphology, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Anatomical Institutes, Via del Pozzo 71, 41124 Modena, Italy.

PMID: 37182755
DOI: 10.1016/j.bone.2023.116790

Abstract

The present letter to editor comments the manuscript entitled "Targeting osteocytes vs osteoblasts" by Y. Kitase and M. Prideaux, where we underlie the importance morphology in choosing Cre experimental models for targeting osteoblasts vs osteocytes.

Keywords: Dynamic osteogenesis (DO); Morphology; Osteoblasts; Osteocytes; Static osteogenesis (SO).

Publication types

Letter
Comment

MeSH terms

Integrases
Osteoblasts*
Osteocytes*
Osteogenesis

Substances

Cre recombinase
Integrases