Persistent oral mucosal lesions preceding diagnosis of Crohn's disease and primary sclerosing cholangitis

Karita Nylund; Jaana Helenius-Hietala; Fredrik Åberg; Jaana Hagström; Hellevi Ruokonen

doi:10.1002/ccr3.7226

Persistent oral mucosal lesions preceding diagnosis of Crohn's disease and primary sclerosing cholangitis

Clin Case Rep. 2023 May 10;11(5):e07226. doi: 10.1002/ccr3.7226. eCollection 2023 May.

Authors

Karita Nylund¹, Jaana Helenius-Hietala¹, Fredrik Åberg², Jaana Hagström^{3

4}, Hellevi Ruokonen¹

Affiliations

¹ Department of Oral and Maxillofacial Diseases HUS Helsinki University Hospital and University of Helsinki Helsinki Finland.
² Department of Transplantation and Liver Surgery HUS Helsinki University Hospital and University of Helsinki Helsinki Finland.
³ Department of Oral Pathology and Radiology, Faculty of Medicine University of Turku Turku Finland.
⁴ Department of Pathology HUS Helsinki University Hospital and University of Helsinki Helsinki Finland.

Abstract

Oral mucosal lesions may persist years before symptoms or diagnosis of inflammatory bowel disease (IBD) and subsequent primary sclerosing cholangitis (PSC). Since a dental practitioner may be the first clinician to suspect IBD with extraintestinal manifestations (EIMs), early referral, and close collaboration with a gastroenterologist are recommended.

Keywords: dentistry; gastroenterology and hepatology; inflammatory bowel disease (IBD); oral medicine.

Publication types

Case Reports