Global trends, gaps, and future agenda in medulloblastoma research: a bibliometric analysis

Childs Nerv Syst. 2023 Nov;39(11):3185-3194. doi: 10.1007/s00381-023-05969-2. Epub 2023 May 13.

Abstract

Background: Medulloblastoma is the most common malignant primary pediatric brain tumor. Over the years, an increase in published research has been observed on this topic. However, there is a lack of analysis on the characteristics and trends and the socioeconomic indicators associated with medulloblastoma research productivity and impact.

Methods: The Scopus database was used to search all articles from inception to 2020. Bibliometric information was obtained from Scopus, and bibliometrics diagrams were created using VOSviewer software. Statistical analysis was performed using the GraphPad Prism software version 7.

Results: A total of 4058 research articles on medulloblastoma research worldwide were included in this study. There has been an increase in published articles, with a steep increase observed in the last decade. The country with the most publications is the USA, with St. Jude Children's Research Hospital as the most productive institution in medulloblastoma research. The articles mainly focused on molecular biology, diagnosis, treatment, prognostic factors for medulloblastoma, and research on other pediatric tumors. The number of collaborations with other countries showed the strongest positive correlation with scientific productivity.

Conclusion: This analysis showed the trend and characteristics of published articles. The results of this study emphasized the need to increase funding for research, support for researchers and physicians, and promote more collaborations with countries and institutions engaged in medulloblastoma research.

Keywords: Brain tumor; Neurosurgery; Oncology; Pediatric cancer; Scientometric analysis.

MeSH terms

  • Bibliometrics
  • Biomedical Research*
  • Cerebellar Neoplasms* / therapy
  • Child
  • Databases, Factual
  • Humans
  • Medulloblastoma* / therapy