Getting off to a good start

Elife. 2023 May 11:12:e88396. doi: 10.7554/eLife.88396.

Abstract

RNA polymerase II transcription can efficiently occur when mouse embryonic stem cells lack TBP and TBP-like proteins, confirming that this initiation factor may not be as essential as once thought.

Keywords: chromosomes; degron; embryonic stem cells; gene expression; genomics; mouse; transcription.

Publication types

  • Editorial

MeSH terms

  • Animals
  • Mice
  • RNA Polymerase II* / metabolism
  • TATA-Box Binding Protein / metabolism
  • Transcription Factors* / metabolism
  • Transcription, Genetic

Substances

  • Transcription Factors
  • TATA-Box Binding Protein
  • RNA Polymerase II