Addisonian pigmentation associated with acute lymphoblastic leukemia: A rare paraneoplastic phenomenon

Pediatr Dermatol. 2023 Nov-Dec;40(6):1112-1114. doi: 10.1111/pde.15341. Epub 2023 May 9.

Abstract

Addisonian pigmentation usually presents with nonspecific symptoms and signs, which are often ignored or misdiagnosed as a sign of other more common diseases. We present a case of 12-year-old child in whom diffuse Addisonian hyperpigmentation of skin was associated with underlying acute lymphoblastic leukemia (B-type), a rare paraneoplastic phenomenon in hematological malignancies.

Keywords: Addisonian pigmentation; acute lymphoblastic leukemia; paraneoplastic dermatosis.

Publication types

  • Case Reports

MeSH terms

  • Child
  • Humans
  • Hyperpigmentation* / etiology
  • Pigmentation
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma* / complications
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma* / diagnosis
  • Skin